Surface-Enhanced Raman Spectroscopy Based Quantitative Bioassay on Aptamer-Functionalized Nanopillars Using Large-Area Raman Mapping
نویسندگان
چکیده
منابع مشابه
Biosensing Based on Surface-Enhanced Raman Spectroscopy by Using Metal Nanoparticles
Surface-enhanced Raman spectroscopy (SERS) is a promising tool in the analytical science because it provides good selectivity and sensitivity without the labeling process required by fluorescence detection. This technique consists of locating the target analyte on nanometer range of roughed Au-nanoparticles. The presence of the metal nanoparticles provides a tremendous enhancement to the result...
متن کاملLarge area fabrication of leaning silicon nanopillars for surface enhanced Raman spectroscopy.
Using a simple two step fabrication process substrates with a large and uniform Raman enhancement, based on flexible free standing nanopillars can be manufactured over large areas using readily available silicon processing equipment.
متن کاملSurface Enhanced Raman Spectroscopy
Raman spectroscopy is the use of inelastic scattering of light to probe various properties of molecules and materials. Incoming photons interact with the electron cloud of the molecular bonds and inelastically scatter. During this scattering the energy of the incoming photon is shifted to red or blue depending on the particular process. This phenomenon is called Raman scattering and was discove...
متن کاملSurface-enhanced Raman spectroscopy.
The ability to control the size, shape, and material of a surface has reinvigorated the field of surface-enhanced Raman spectroscopy (SERS). Because excitation of the localized surface plasmon resonance of a nanostructured surface or nanoparticle lies at the heart of SERS, the ability to reliably control the surface characteristics has taken SERS from an interesting surface phenomenon to a rapi...
متن کاملQuantitative label-free RNA detection using surface-enhanced Raman spectroscopy.
Surface-Enhanced Raman Spectroscopy (SERS) was performed to detect label-free RNA. We defined conditions which make it possible to probe the four bases of RNA, in single strands of polyadenosine (pA), polyuridine (pU), polycytosine (pC) and polyguanosine (pG). We therefore present below a quantitative analysis of mixtures of non-hybridized single strands, based on the deconvolution of the SERS ...
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ژورنال
عنوان ژورنال: ACS Nano
سال: 2013
ISSN: 1936-0851,1936-086X
DOI: 10.1021/nn401199k